Knowledge-based Query Expansion in Real-Time Microblog Search

Since the length of microblog texts, such as tweets, is strictly limited to 140 characters, traditional Information Retrieval techniques suffer from the vocabulary mismatch problem severely and cannot yield good performance in the context of microblogosphere. To address this critical challenge, in this paper, we propose a new language modeling approach for microblog retrieval by inferring various types of context information. In particular, we expand the query using knowledge terms derived from Freebase so that the expanded one can better reflect users' search intent. Besides, in order to further satisfy users' real-time information need, we incorporate temporal evidences into the expansion method, which can boost recent tweets in the retrieval results with respect to a given topic. Experimental results on two official TREC Twitter corpora demonstrate the significant superiority of our approach over baseline methods.Comment: 9 pages, 9 figure

Patchouli Alcohol Modulates the Pregnancy X Receptor/Toll-like Receptor 4/Nuclear Factor Kappa B Axis to Suppress Osteoclastogenesis

The incidence of osteoporosis, which is primarily characterized by plethoric osteoclast (OC) formation and severe bone loss, has increased in recent years. Millions of people worldwide, especially postmenopausal women, suffer from osteoporosis. The drugs commonly used to treat osteoporosis still exist many disadvantages, but natural extracts provide options for the treatment of osteoporosis. Therefore, the identification of cost-effective natural compounds is important. Patchouli alcohol (PA), a natural compound extracted from Pogostemon cablin that exerts anti-inflammatory effects, is used as a treatment for gastroenteritis. However, no research on the use of Patchouli alcohol in osteoporosis has been reported. We found that PA dose-dependently inhibited the receptor activator of nuclear factor kappa-B ligand (RANKL)-induced formation and function of OCs without cytotoxicity. Furthermore, these inhibitory effects were reflected in the significant effect of PA on the NF-κB signaling pathway, as PA suppressed the transcription factors NFATc1 and c-Fos. We also determined that PA activated expression of the nuclear receptor pregnane X receptor (PXR) and promoted the PXR/Toll-like receptor 4 (TLR4) axis to inhibit the nuclear import of NF-κB (p50 and p65). Additionally, PA exerted therapeutic effects against osteoporosis in ovariectomized (OVX) mice, supporting the use of PA as a treatment for osteoporosis in the future

In-Line and Off-Axis Hybrid Digital Holographic Imaging Method Based on Off-Axis Hologram Constraints

We put forward a novel hybrid iterative algorithm to improve the imaging quality of digital holography. An off-axis hologram is added to the iteration process via interference and inverse interference process and becomes part of the constraints. A frequency domain filter varying with the number of iterations is used to improve the competitive advantage of low frequency information in the early iterations, while retaining the high frequency information. In practical applications, an additional iterative process is used after averaging filtering to suppress the influence of the imperfect consistency between the reconstructed reference wave and the actual reference wave. Numerical simulations and experiments show that image reconstruction may be significantly improved compared to the conventional method

Effect of Ellipsoidal Modulus and Internal Pressure on Bearing Capacity of Thrust-Bearing Aft Dome

In order to analyse the effect of ellipsoidal modulus and internal pressure on bearing capacity of thrust-bearing aft dome, we obtain the stress and strain distribution and bearing capacity of 1.6, 1.4 and 1.0 modulus ellipsoidal aft dome under 0MPa~0.98MPa internal pressure and engine thrust by finite element method. We find as the modulus decreases, the bearing capacity of the ellipsoidal aft dome increases, and as internal pressure decreases, within the engineering range (0~0.98MPa), the bearing capacity increases. The conclusion can provide a guidance for the design of thrust-bearing aft dome

Perceiving Excitation Characteristics from Interactions between Field Road and Vehicle via Vibration Sensing

When agricultural vehicles operate in the field, the soft road excitation makes it difficult to measure the vehicle vibration. A camera-accelerator system can solve this issue by utilizing computer vision information; however, the relationship between the field road surface and the vehicle vibration response remains an unsolved problem. This study aims to investigate the correlation of the soft road excitation of different long-wave surfaces with the vehicle vibration response. Vibration equation between the vehicle and soft road surface system was established to produce an effective roughness model of the field soft road surface. In order to simulate the vehicle vibration state under different long-wave road surfaces, the soil rectangular pits with 21 kinds of different spans and depths were applied to the road surfaces, and a tractor vibration test system was built for vibration test. The frequency spectrum analysis was performed for the vibration response and the roughness signals of the road surfaces. The results showed that coefficient (R2) of frequency correlation between the roughness excitation and the original unevenness at the excitation point at the rear end of the rectangular soil pit fell within 0.9641∼0.9969. The main frequency band of the vibration response fell within 0∼3 Hz, and the phenomenon of quadruple frequency existed. The correlation of roughness excitation with quadruple frequency fell within 0.992165∼1. The primary excitation points were located at the rear end of the rectangular soil pit. In addition, it also indicated that when the vehicle was driven without autonomous power, the vehicle vibration frequency mainly depended on the excitation frequency of the field road surface and the frequency at the maximum vehicle vibration intensity was 2 or 3 times of that at the maximum field soft road excitation. These findings may provide a reference for optimal design of vibration reduction and control for agricultural vehicles

Candy box technique for the fixation of inferior pole patellar fractures: finite element analysis and biomechanical experiments

Abstract Background Maintaining effective reduction and firm fixation in inferior pole patellar fractures is a highly challenging task. There are various treatment methods available; although tension-band wiring combined with cerclage wiring (TBWC) is the mainstream approach, its effectiveness is limited. Herein, we propose and evaluate a new technique called candy box (CB), based on separate vertical wiring (SVW), for the treatment of inferior pole patellar fractures. Specifically, we provide biomechanical evidence for its clinical application. Methods Five fixation models were built: SVW combined with cerclage wiring (SVWC); TBWC; modified SVW with the middle (MSVW-A) or upper (MSVW-B) 1/3 of the steel wire reserved, and CB. A finite element analysis was performed to compare the displacement and stress under 100-N, 200-N, 300-N, 400-N and 500-N force loads. Three-dimensional printing technology was utilized to create fracture models, and the average displacement of each model group was compared under a 500-N force. Results The results of the finite element analysis indicate that CB technology exhibits significantly lower maximum displacement, bone stress, and wire stress compared to that with other technologies under different loads. Additionally, in biomechanical experiments, the average force displacement in the CB group was significantly smaller than that with other methods under a 500-N force (P < 0.05). Conclusions CB technology has the potential to overcome the limitations of current techniques due to its superior biomechanical characteristics. By incorporating early functional exercise and ensuring strong internal fixation, patient prognosis could be enhanced. However, further clinical trials are needed to fully evaluate the therapeutic effects of CB technology